DRUGS BANNED IN INDIA

A number of individual drugs as well as fixed dose combinations are banned in India due to various reasons of safety & rationality. Let me give you an overview how the scenario.
Drugs undergo rigorous testing before they are introduced into the market. They are first tested on animals and then on human beings during clinical trials.  The efficacy as well as safety profiles of the drug are tested.   In spite of this, some adverse effects of drugs appear only after the drug is used on the general population.  These adverse effects are detected though a process of regular monitoring after the drug is released called pharmacovigilance.  If the adverse effects are severe nature or the risks of using the drug outweigh the benefits, or if the drug is ineffective, the country may ban the drug or the Drug Company may itself voluntarily withdraw the drug.  Some drugs may cause adverse effects only when combined with particular drugs.  In such cases, only the fixed dose combination is banned and not the individual drugs.
A number of single drugs as well as fixed dose combinations have been banned for manufacture, marketing and distribution in India. Some drugs banned in India are mentioned below:

Fenfluramine and dexfenfluramine
Fenfluramine and dexfenfluramine were used to treat obesity.  They were widely used in slimming centers.  However, they were withdrawn due to reports of diseases of heart valves, fibrosis of the heart and pulmonary hypertension.  The combination of Fenfluramine and Phenteramine, another weight loss pill was particularly notorious for causing heart valve problems and sudden death.

Rimonabant
Rimonabant was particularly effective in causing weight loss.  It inhibited the action of substances called cannabinoids in the brain.  It has been withdrawn due to serious side effects like depression, suicidal tendencies and seizures.

Sibutramine
Sibutramine is a weight loss pill that has been recently withdrawn from the market since it caused heart related side effects.

Astemizole and Terfinadine  
Astemizole and Terfinadine are antihistamines that were used to treat allergies.  They were prohibited for use since they could cause a heart condition called polymorphic ventricular tachycardia and even death when used in high doses or with drugs like erythromycin, Clarithromycin and  Ketoconazole.

Phenformin
Phenformin is an antidiabetic drug similar to Metformin.  It has been prohibited for use since it carries a high risk of lactic acidosis.

Rofecoxib and Valdecoxib
Rofecoxib and valdecoxib were popular painkillers that were used for arthritis and other painful conditions.  They resulted in pain relief without causing gastric side effects.  However, they were withdrawn due to concerns of heart attack and stroke with their use.

Rosiglitazone
Rosiglitazone is a drug used in the treatment of type 2 diabetes. It has been prohibited due to an increased risk of heart attacks.

Gatifloxacin
Gatifloxacin is an antibiotic whose use as an oral and injectable drug has been recently withdrawn in India.  This is due to its risk for severe hyperglycemia or high blood sugar levels in the elderly.

Tegaserod
Tegaserod is a drug that is used to treat patients with irritable bowel syndrome with predominantly constipation. It was withdrawn from the market since patients taking this drug showed increased incidence of heart attack and stroke.

Comments :

  • cartierbraceletlove This sounds delicious and the photos are gorgeous! Thanks for sharing. love armband gold Fälschung [url=http://www.clovejs.ru/]love armband gold Fälschung[/url]
    Posted by : love armband gold Fälschung on 18 Jan 2017
  • cartierbraceletlove I’d argue that the Gimp in Pulp Fiction is more like The Palestinian Authority in the West Bank, with Gaza being Butch and Marsellus, since the villains try to use the Gimp to guard their prisoner. Even though the Gimp is also a victim he has been enslaved and does the bidding of his masters. In the film he turns out to be an ineffectual minion and we can only hope that the Gazans manage the same trick of Butch’s escape from bondage. rolex day date or rose faux [url=http://www.movement-watch.cn/replica-rolex-day-date-c148/]rolex day date or rose faux[/url]
    Posted by : rolex day date or rose faux on 18 Jan 2017
  • cartierbraceletlove I would like to thnkx for the efforts you have put in writing this web site. I'm hoping the same high-grade website post from you in the upcoming as well. Actually your creative writing skills has encouraged me to get my own web site now. Actually the blogging is spreading its wings quickly. Your write up is a good example of it. cartier gold armreif [url=http://www.clovejs.ru/cartier-love-bracelet-replica-c134/]cartier gold armreif[/url]
    Posted by : cartier gold armreif on 18 Jan 2017
  • cartierbraceletlove I had been wondering if you ever considered replacing the page layout of your site? Its well written; I enjoy what youve got to state. But maybe you could include a little more in the way of content so people could connect to it better. You have got a great deal of text for only having one or two graphics. Maybe you could space it out better? bracelet cartier vis pas cher [url=http://www.bestcalovebracelet.cn/fr/r%C3%A9plique-cartier-love-bracelet-en-or-rose-avec-des-diamants-et-des-tournevis-p-185.html]bracelet cartier vis pas cher[/url]
    Posted by : bracelet cartier vis pas cher on 18 Jan 2017
  • cartierbraceletlove OH EM GEE! I NEED that lipstick! I looooooove this entire collection. cartier bracelet love occasion replique [url=http://www.fashionlovebangle.cn/fr/]cartier bracelet love occasion replique[/url]
    Posted by : cartier bracelet love occasion replique on 18 Jan 2017
  • cartierbraceletlove The commercial reminds me of when I was getting ready to travel to the Soviet Union. Nearly everyone told me to bring a roll of toilet paper because it was one of those items that was always in a shortage and people had to stand in lines to get it. I just dismissed all of this as being an urban legend and took none with me. bracelet cartier taille 16 replica [url=http://www.bestcalovebracelet.cn/fr/]bracelet cartier taille 16 replica[/url]
    Posted by : bracelet cartier taille 16 replica on 18 Jan 2017
  • I see your site needs some unique & fresh content. Writing manually is time consuming, but there is solution for this. Just search for - Masquro's strategies
    Posted by : PhillipqpTfv on 17 Mar 2017

Leave a Replay

Make sure you enter the(*)required information where indicate.HTML code is not allowed