CORTIS - Hydrocortisone 100 mg

Category:- Hormones | Type:- Injection

COMPOSITION:

Each vial contains.

Hydrocortisone Sodium Succinate USP 
Eq. toHydrocortisone 100 mg 
 

PHARMACOLOGICAL CLASSIFICATION: 
A.21.5.1-Corticosteroids and analogues. 
A.34 --Others -Diluent 
 

PHARMACOLOGICAL ACTION: 
Hydrocortisone sodium succinate acts by controlling the rate of protein synthesis. It forms a steroid­ receptor complex with receptor proteins, moves into the nucleus where it binds the chromatin and thus directs the genetic apparatus to transcribe RNA. It also delays the mineralocorticoid activity. 
 

INDICATIONS: 
As substitution therapy in the treatment of adrenal insufficiency states, where high levels of hydrocortisone are required rapidly. In patients with known or suspected adrenal insufficiency prior to surgery, or if  shock, severe trauma or other stress conditions occur. Hydrocortisone sodium succinate is also used for the symptomatic relief of inflammatory conditions and as an immunosuppressant. 
 

CONTRA-INDICATIONS: 
Hypersensitivity to corticosteroids. Tuberculosis. Ocular herpes simplex. Primary glaucoma. Acute psychosis and psychoneurosis. Systemic infection. Peptic ulcer. Osteoporosis.