NANDROLONE - Nandrolone Decanoate 50mg

Category:- Hormones | Type:- Injection

Each ml contains: Nandrolone Decanoate USP 50 mg

Indications and usage:
Nandrolone is indicated for the management of the anaemia of renal Insufficiency and has been shown to increase haemoglobin and red cell mass.
 

Contraindications:
1. Known hypersensitivity to the drug.
2. Male patients with carcinoma of the breast or with known or suspected carcinoma of the prostate.
3. Carcinoma of the breast in females with hypercaleemia androgenic anabolic steroids may stimulate osteolytic resorption of bones.
4. Pregnancy, because of masculinisation of the foetus.
5. Nephrosis or the nephrotic phase of nephrifis.
6. Patients with serious cardiac, hepatic or renal disease.
 

Drug Interactions:
Anticoagulants. Anabolic steroids may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may have to be decreased in order to maintain the prothrombin time at the desired therapeutic level. Patients receiving oral anticoagulant therapy require close monitoring, especially when anabolic steroids are started or stopped Anabolic steroids may decrease levels of thyroxine-binding globulin, resulting In decreased total 14 serum levels and increased resin uptake of T3 and 14. Free thyroid hormone levels remain unchanged.

Overdosage: 

There have been no reports of acute overdosage with the anabolics.
 

Adverse reactions:
Hepatic: Choiestatic jaundice with, rarely, hepatic necrosis and death. Hepatocellular neothasms and peliosis hepatitis have been reported in association with long-term use of androgenic anabolic steroids, particularly those that are 17-alpha-alkylated.
In men: Prepubertal: Phallic enlargement and increased frequency of erections. 

Postpubertal: Inhibition of testicular function, testicular atrophy and otigospermia, impotence, chronic priapism, epididymitis and bladder irritability.

In women: Clitoral enlargement, menstrual irregularities.
In both sexes: Increased or decreased libido.
hormone levels remain unchanged.
CNS: Habituation, excitation, insomnia, clepreseion. Gastrointestinal: Nausea, vomiting, diarrhea.

Hematologic: Bleeding in patients on concomitant anticoagulant therapy (see Precaution, Drug Interactions). Breast Gynecomastia.

Larynx: Deepening of the vioce in women.

Hair: Hirsutism and male pattern baldness in women.
Skin: Acne (especially in women and prepubertal boys).
Skeletal: Premature closure of epiphyses M children (see Precaution, Pediatric Use)

Fluid and electrolytes: Edema retention of serum electrolytes (sodium chloride, potassium phosphate, calcium).
Metabolic/endocrine: Decreased glucose tolerance, increased serum levels of low-density lipoproteins and decreased levels of high-density lipoproteins, increased creatine and creatinine excretion, increased serum levels of creatine phosphokinase. Some virilizing changes in women are irreversible even after
prompt discontinuance of therapy and are not prevented by concomitant use of estrogens.

Precautions:
Nandrolone should be used with caution in patients with any disease, especially cancer of the prostate or breast, liver, heart. Kidney disease, allergy, enlarged prostate. High dosage, long term use of androgens has been related to liver cancer. This drug should not be used during pregnancy or lactation. Females should be monitored for signs virilization, such as deepening of the voice. facial haft, acne, menstrual irregularity or clitoral enlargement, consult the doctor promptly if any of these symptoms occur. Use in children should not be recommended due to the possibility this drug may have undesirable effects related to the growth of the child. It should be used with extreme caution in geriatric men because they are at higher risk for developing enlarged prostates or prostate cancer when using this medication.

Dosage and adminstration:
Nandrolone is intended only for deep intramuscular injection preferably into the gluteal muscle. Dosage should be based on therapeutic response and consideration of the benefit/risk ratio. Duration of therapy will depend on the response of the condition and the appearance of adverse reactions. If
possible, therapy should be intermittent. Nandrolone should be regarded as adjunetive therapy and adequate quantities of nutrients should be consumed in order to obtain maximal therapeutic effects. Anaemia of renal disease.
A dose of 50-100 mg per week Nandrolone is recommended for women and 50-200 mg per week for men. Drug therapy should be discontinued if no hematologic improvement is seen within the first six months. When used in the treatment of renal insufficiency, adequate iron intake is required for maximal
response. For children from 2 to 13 years of age, the average dose is 25-50 mg every3 to 4 weeks, Warnings: Peliosis hepatitis, a condition in which liver and sometimes splenic tissue is replaced with blood-filled cysts, occurred in patients receiving androgenic anabolic steroids. The condition may not be
recognized until life-threatening liver failure or intra-abdominal haemorrhage develops. Lesions completely resolve upon discontinuation. Liver cell tumour, often benign and androgen-dependent but sometimes malignant, have occurred, Drug discontinuation often results in regression or cessation of tumour growth. Hepatic tumours associated with androgens or anabolic steroids may be silent until life-threatening, intra-abdominal haemorrhage develops. Blood lipid  changes, Including decreased HDL and increased LDL, associated with increased risk of atherosclerosis are seen in some patients treated with androgens and anabolic steroids.

How supplied
Nandrolone is supplied in 1ml ampoule & should be stored at controlled room temperatures below 30°C and protected from light. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration. If it has expired or is damaged, return it to your pharmacist for
disposal.

Abuse in Sports
Abuse of this product in sports is highly discouraged. Cooper pharma does not take any responsibility for use of this product for any other purpose. This product should be used under proper medical supervision.

Keep out of the reach and sight of children. 

Effect of materials on plants or animals: This product may be harmful to contaminated plant and animal life.

Effect of chemicals on aquatic life: This product may be harmful to aquatic plant and animal life in contaminated bodies of water, especially if released in large quantities.
 

Manufactured by:
COOPER PHARMA LIMITED